SNAPIN

Across TCGA patient cohorts, SNAPIN protein abundance is significantly associated with the RNA expression of many other genes, with 9,776 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNAPIN-associated genes across cancer lineages are TREM1, CXCL8, and H2AC13. Each is linked with SNAPIN in more than 3 cancer types. Because this analysis shows association rather than direction, both SNAPIN-to-partner and partner-to-SNAPIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNAPIN versus TREM1 in LUAD, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAPIN→partner) and Y-score (partner→SNAPIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TREM1 →	-0.954	-0.144	<.001	.001	3	4
HNSC	CXCL8 →	-1.463	-0.212	<.001	<.001	3	4
HNSC	H2AC13 →	-1.606	-0.225	.004	.003	3	4
HNSC	H2AC12 →	-2.012	-0.283	.001	<.001	3	4
HNSC	H3C10 →	-1.178	-0.216	.005	.002	3	4
GBM	H3C2 →	-1.698	-0.312	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,776 associations by consensus.

SNAPIN vs TREM1 — LUAD

Explore this scatter interactively →