SNAPIN

Across TCGA cell cohorts, SNAPIN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,326 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SNAPIN-associated GO terms across cancer lineages are Regulation of late endosome to lysosome transport, Regulation of vacuolar transport, and Iron-sulfur cluster assembly. Each is linked with SNAPIN in more than 10 cancer types. Because this analysis shows association rather than direction, both SNAPIN-to-partner and partner-to-SNAPIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of late endosome to lysosome transport grouped by SNAPIN-low versus SNAPIN-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAPIN→partner) and Y-score (partner→SNAPIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of late endosome to lysosome transport →	+0.148	+0.523	<.001	<.001	3	11
CNS	Regulation of vacuolar transport →	+0.148	+0.523	<.001	<.001	3	11
STOMACH	Iron-sulfur cluster assembly →	+0.080	+0.704	.001	.002	3	9
STOMACH	Metallo-sulfur cluster assembly →	+0.080	+0.704	.001	.002	3	9
STOMACH	Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →	+0.098	+0.712	.005	.004	3	9
OESOPHAGUS	Mononuclear cell migration →	-0.105	-0.545	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,326 associations by consensus.

Regulation of late endosome to lysosome transport by SNAPIN expression — CNS

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