SNAPC5P1

Across TCGA patient cohorts, SNAPC5P1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNAPC5P1-associated genes across cancer lineages are MTHFD2P5, RPSAP60, and RPS15AP27. Each is linked with SNAPC5P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAPC5P1-to-partner and partner-to-SNAPC5P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTHFD2P5 grouped by SNAPC5P1-low versus SNAPC5P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAPC5P1→partner) and Y-score (partner→SNAPC5P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTHFD2P5 →	+0.153	+4.221	.003	.003	3	1
UCEC	RPSAP60 →	+0.161	+4.717	<.001	.001	3	1
UCEC	RPS15AP27 →	+0.176	+3.748	<.001	.008	3	1
UCEC	CCR12P →	+0.181	+4.296	.003	.003	3	1
UCEC	ATP6V1E1P2 →	+0.231	+3.661	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

MTHFD2P5 by SNAPC5P1 expression — UCEC

Explore this box plot interactively →