SNAP23

Across TCGA cell cohorts, SNAP23 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,731 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SNAP23-associated GO terms across cancer lineages are Post-Golgi vesicle-mediated transport, Vesicle-mediated transport to the plasma membrane, and Regulation of translation at postsynapse, modulating synaptic transmission. Each is linked with SNAP23 in more than 12 cancer types. Because this analysis shows association rather than direction, both SNAP23-to-partner and partner-to-SNAP23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-Golgi vesicle-mediated transport grouped by SNAP23-low versus SNAP23-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAP23→partner) and Y-score (partner→SNAP23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Post-Golgi vesicle-mediated transport →	+0.052	+0.678	.003	.004	3	13
BLOOD_Myeloma	Vesicle-mediated transport to the plasma membrane →	+0.060	+0.836	.002	<.001	3	13
LUNG_SCLC	Regulation of translation at postsynapse, modulating synaptic transmission →	+0.114	+0.994	.004	.009	2	13
LARGE_INTESTINE	Cytosolic transport →	+0.067	+0.810	<.001	<.001	3	12
BLOOD_Myeloma	Endocytic recycling →	+0.063	+0.725	<.001	<.001	2	13
PANCREAS	Endosomal transport →	+0.050	+1.051	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,731 associations by consensus.

Post-Golgi vesicle-mediated transport by SNAP23 expression — LARGE_INTESTINE

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