Across TCGA patient cohorts, SNAI3 protein abundance is significantly associated with the RNA expression of many other genes, with 425 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SNAI3-associated genes across cancer lineages are HMOX1, KCTD17, and SIX4. Each is linked with SNAI3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAI3-to-partner and partner-to-SNAI3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAI3→partner) and Y-score (partner→SNAI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HMOX1 →	+0.525	+0.315	.002	.003	3	1
CCRCC	KCTD17 →	-0.415	-0.433	.003	.001	3	1
CCRCC	SIX4 →	-0.325	-0.445	.005	.001	3	1
CCRCC	RIMS4 →	-0.045	-0.286	.008	.009	3	1
CCRCC	MYL9 →	-0.706	-0.394	<.001	<.001	3	1
CCRCC	CHRDL1 →	-1.598	-0.505	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 425 associations by consensus.

Exploration

SNAI3 survival (RNA) · tumor vs normal (RNA) · all SNAI3 data types