Across TCGA patient cohorts, SNAI3 mutation is significantly associated with the RNA expression of many other genes, with 160 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNAI3-associated genes across cancer lineages are CENPN, NCAPH2, and MTCO3P41. Each is linked with SNAI3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAI3-to-partner and partner-to-SNAI3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAI3→partner) and Y-score (partner→SNAI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPN →	+1.011	+3.343	<.001	.005	3	2
UCEC	NCAPH2 →	+0.760	+3.338	<.001	.005	3	2
BLCA	MTCO3P41 →	+0.082	+4.899	<.001	.005	3	2
BLCA	RN7SKP107 →	+0.123	+6.040	<.001	.001	3	2
UCEC	OTULIN →	+0.537	+3.332	.002	.005	3	1
UCEC	TBRG1 →	+0.456	+3.375	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 160 associations by consensus.

Exploration

SNAI3 survival (RNA) · tumor vs normal (RNA) · all SNAI3 data types