SNAI3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNAI3 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNAI3-associated genes across cancer lineages are MEK1, Notch1, and Di-Ras3. Each is linked with SNAI3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAI3-to-partner and partner-to-SNAI3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAI3→partner) and Y-score (partner→SNAI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMEK1 →+0.520+3.169.009.02032
UCECNotch1 →+0.215+3.169.005.02032
UCECDi-Ras3 →-0.180-3.169.026.02032
UCECJNK_pT183_Y185 →-0.189-3.156.041.02031
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration