Across TCGA cell cohorts, SNAI3 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNAI3-associated genes across cancer lineages are IQCF5, RESP18, and PRDM7. Each is linked with SNAI3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAI3-to-partner and partner-to-SNAI3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAI3→partner) and Y-score (partner→SNAI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IQCF5 →	+0.124	+5.201	<.001	.006	3	1
OVARY	RESP18 →	+0.038	+5.196	<.001	.005	3	1
LARGE_INTESTINE	PRDM7 →	+0.221	+3.302	<.001	.006	3	1
LARGE_INTESTINE	BPIFA1 →	+0.105	+3.425	.004	<.001	3	1
LARGE_INTESTINE	MSH4 →	+0.261	+3.464	.002	.004	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

SNAI3 survival (RNA) · tumor vs normal (RNA) · all SNAI3 data types