SNAI1

Across TCGA patient cohorts, SNAI1 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,316 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNAI1-associated proteins across cancer lineages are REEP3_Y209, RNPC3, and SAP30BP_S113. Each is linked with SNAI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAI1-to-partner and partner-to-SNAI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNAI1 versus REEP3_Y209 in BRCA, with a Pearson correlation of -0.96.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAI1→partner) and Y-score (partner→SNAI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	REEP3_Y209 →	-0.778	-1.253	<.001	.005	3	1
BRCA	RNPC3 →	+0.386	+1.266	<.001	.004	3	1
UCEC	SAP30BP_S113 →	+0.460	+1.219	<.001	.004	2	2
BRCA	SIN3A_T287 →	+0.359	+1.490	.003	.005	3	1
BRCA	JPT1_S79 →	+0.734	+1.670	.002	.004	3	1
UCEC	DDX17_S64 →	-1.020	-1.099	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,316 associations by consensus.

SNAI1 vs REEP3_Y209 — BRCA

Explore this scatter interactively →