SMYD5

Across TCGA patient cohorts, SMYD5 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,944 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SMYD5-associated proteins across cancer lineages are TBCB, UNC13D, and XPO1. Each is linked with SMYD5 in more than 5 cancer types. Because this analysis shows association rather than direction, both SMYD5-to-partner and partner-to-SMYD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMYD5 versus TBCB in COAD, with a Pearson correlation of 0.44.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMYD5→partner) and Y-score (partner→SMYD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TBCB →	+0.434	+0.492	<.001	<.001	3	5
GBM	UNC13D →	-0.354	-0.240	<.001	<.001	3	5
LSCC	XPO1 →	+0.249	+0.256	.002	.001	3	5
COAD	ATOX1 →	+0.356	+0.464	.001	<.001	3	5
CCRCC	CNBP →	+0.550	+0.296	<.001	<.001	3	5
UCEC	AIP →	+0.297	+0.229	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,944 associations by consensus.

SMYD5 vs TBCB — COAD

Explore this scatter interactively →