SMU1

Across TCGA patient cohorts, SMU1 protein abundance is significantly associated with the protein abundance of many other proteins, with 24,353 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMU1-associated proteins across cancer lineages are SUPT16H, SUPT6H, and TCERG1. Each is linked with SMU1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SMU1-to-partner and partner-to-SMU1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMU1 versus SUPT16H in GBM, with a Pearson correlation of 0.76.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMU1→partner) and Y-score (partner→SMU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SUPT16H →	+0.533	+0.256	<.001	<.001	3	10
GBM	SUPT6H →	+0.310	+0.284	<.001	<.001	3	10
GBM	TCERG1 →	+0.357	+0.280	<.001	<.001	3	10
GBM	TPR →	+0.334	+0.278	<.001	<.001	3	10
BRCA	U2SURP →	+0.411	+0.288	<.001	<.001	3	10
GBM	WDR5 →	+0.368	+0.253	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,353 associations by consensus.

SMU1 vs SUPT16H — GBM

Explore this scatter interactively →