Across TCGA patient cohorts, SMTNL1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,274 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SMTNL1-associated genes across cancer lineages are FNDC1, RAB3IP, and RFPL3. Each is linked with SMTNL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMTNL1-to-partner and partner-to-SMTNL1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMTNL1→partner) and Y-score (partner→SMTNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FNDC1 →	+2.324	+1.819	<.001	<.001	3	2
LSCC	RAB3IP →	-1.091	-0.946	.001	.009	3	2
OV	RFPL3 →	-0.192	-0.759	.003	.003	3	1
OV	HSPB1P2 →	-1.785	-0.760	.003	.003	3	1
LUAD	STEAP1B →	+0.552	+1.702	.001	.007	3	1
LUAD	PTGR1 →	-2.182	-1.965	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,274 associations by consensus.

Exploration

SMTNL1 survival (RNA) · tumor vs normal (RNA) · all SMTNL1 data types