SMR3A

Across TCGA patient cohorts, SMR3A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,008 significant associations in total. THCA shows the largest number of these associations.

The most reproducible SMR3A-associated GO terms across cancer lineages are Regulation of epithelial cell migration, Positive regulation of cell-substrate adhesion, and Embryonic eye morphogenesis. Each is linked with SMR3A in more than 8 cancer types. Because this analysis shows association rather than direction, both SMR3A-to-partner and partner-to-SMR3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of epithelial cell migration grouped by SMR3A-low versus SMR3A-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMR3A→partner) and Y-score (partner→SMR3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of epithelial cell migration →	+0.056	+0.162	<.001	.003	2	9
ESCA	Positive regulation of cell-substrate adhesion →	+0.071	+0.134	<.001	.002	3	8
ESCA	Embryonic eye morphogenesis →	+0.059	+0.130	<.001	.003	3	8
ESCA	Embryonic camera-type eye morphogenesis →	+0.064	+0.163	<.001	.002	3	8
ESCA	Cardiac septum morphogenesis →	+0.048	+0.137	<.001	.001	3	8
ESCA	Heart trabecula morphogenesis →	+0.069	+0.239	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,008 associations by consensus.

Regulation of epithelial cell migration by SMR3A expression — ESCA

Explore this box plot interactively →