Across TCGA patient cohorts, SMOC1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,141 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMOC1-associated genes across cancer lineages are SLC16A14, EYS, and ARMH4. Each is linked with SMOC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SMOC1-to-partner and partner-to-SMOC1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMOC1→partner) and Y-score (partner→SMOC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SLC16A14 →	+1.077	+0.831	<.001	<.001	3	4
GBM	EYS →	+0.664	+1.372	.002	<.001	3	4
CCRCC	ARMH4 →	+0.577	+0.421	.003	.005	3	4
CCRCC	SFRP1 →	+1.936	+0.765	<.001	<.001	3	4
GBM	PDE1A →	+0.850	+0.986	<.001	<.001	3	3
GBM	SLC8A3 →	+0.904	+1.118	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,141 associations by consensus.

Exploration

SMOC1 survival (RNA) · tumor vs normal (RNA) · all SMOC1 data types