SMKR1

Across TCGA cell cohorts, SMKR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,029 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SMKR1-associated GO terms across cancer lineages are Nucleotide biosynthetic process, RNA localization to Cajal body, and RNA localization to nucleus. Each is linked with SMKR1 in more than 11 cancer types. Because this analysis shows association rather than direction, both SMKR1-to-partner and partner-to-SMKR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide biosynthetic process grouped by SMKR1-low versus SMKR1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMKR1→partner) and Y-score (partner→SMKR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Nucleotide biosynthetic process →	+0.055	+1.543	<.001	<.001	3	12
BLOOD_Myeloma	RNA localization to Cajal body →	+0.101	+2.236	<.001	<.001	3	11
BLOOD_Myeloma	RNA localization to nucleus →	+0.101	+2.236	<.001	<.001	3	11
LUNG_SCLC	Mitochondrial membrane organization →	+0.074	+1.219	.001	.004	3	10
LUNG_SCLC	Protein transmembrane transport →	+0.052	+1.503	.003	<.001	3	10
URINARY_TRACT	Hydrogen peroxide metabolic process →	+0.143	+1.452	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,029 associations by consensus.

Nucleotide biosynthetic process by SMKR1 expression — LUNG_SCLC

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