SMIM8

Across TCGA patient cohorts, SMIM8 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,351 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMIM8-associated proteins across cancer lineages are PM20D2, SYNCRIP, and SCAF8. Each is linked with SMIM8 in more than 5 cancer types. Because this analysis shows association rather than direction, both SMIM8-to-partner and partner-to-SMIM8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM8 versus PM20D2 in OV, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM8→partner) and Y-score (partner→SMIM8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PM20D2 →	+0.718	+0.396	.002	.001	3	6
OV	SYNCRIP →	+0.265	+0.328	<.001	<.001	3	5
LSCC	SCAF8 →	+0.250	+0.515	<.001	.001	3	5
LSCC	HNRNPL →	+0.173	+0.401	<.001	.001	3	5
LSCC	PHF3 →	+0.291	+0.426	<.001	<.001	3	5
BRCA	RNGTT →	+0.413	+0.415	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,351 associations by consensus.

SMIM8 vs PM20D2 — OV

Explore this scatter interactively →