SMIM8

Across TCGA cell cohorts, SMIM8 RNA expression is significantly associated with the RNA expression of many other genes, with 11,243 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SMIM8-associated genes across cancer lineages are ORC3, RNGTT, and CASP8AP2. Each is linked with SMIM8 in more than 16 cancer types. Because this analysis shows association rather than direction, both SMIM8-to-partner and partner-to-SMIM8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM8 versus ORC3 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.70.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM8→partner) and Y-score (partner→SMIM8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	ORC3 →	+1.007	+0.755	<.001	<.001	3	17
BLOOD_Lymphoma	RNGTT →	+1.411	+0.718	<.001	<.001	3	15
BLOOD_Myeloma	CASP8AP2 →	+1.146	+0.636	.002	.009	1	17
OVARY	SENP6 →	+0.910	+0.759	<.001	<.001	3	14
BLOOD_Lymphoma	ZUP1 →	+0.882	+0.729	<.001	<.001	3	14
BLOOD_Lymphoma	MDN1 →	+0.945	+0.532	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,243 associations by consensus.

SMIM8 vs ORC3 — LUNG_NSCLC_LUSC

Explore this scatter interactively →