Across TCGA patient cohorts, SMIM7 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMIM7-associated genes across cancer lineages are lymphatic Endothelial cells, mv Endothelial cells, and Hepatocytes. Each is linked with SMIM7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM7-to-partner and partner-to-SMIM7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM7→partner) and Y-score (partner→SMIM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	lymphatic Endothelial cells →	-0.024	-3.129	.034	.019	3	1
UCEC	mv Endothelial cells →	-0.025	-3.000	.030	.036	3	1
UCEC	Hepatocytes →	-0.012	-2.990	.018	.022	2	1
UCEC	Plasma cells →	-0.026	-3.057	.013	.020	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

SMIM7 survival (RNA) · tumor vs normal (RNA) · all SMIM7 data types