Across TCGA cell cohorts, SMIM7 mutation is significantly associated with the mutation status of many other genes, with 99 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SMIM7-associated genes across cancer lineages are VSTM5, EVPLL, and TAS2R41. Each is linked with SMIM7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM7-to-partner and partner-to-SMIM7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM7→partner) and Y-score (partner→SMIM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	VSTM5 →	+5.523	+5.523	.003	.003	1	1
LARGE_INTESTINE	EVPLL →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	TAS2R41 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	MRPL20 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	TTC4 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	PINX1 →	+4.523	+5.087	.006	.006	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 99 associations by consensus.

Exploration

SMIM7 survival (RNA) · tumor vs normal (RNA) · all SMIM7 data types