SMIM36

Across TCGA patient cohorts, SMIM36 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,698 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SMIM36-associated GO terms across cancer lineages are Spindle assembly, Multicellular organism growth, and Mitotic G2/M transition checkpoint. Each is linked with SMIM36 in more than 16 cancer types. Because this analysis shows association rather than direction, both SMIM36-to-partner and partner-to-SMIM36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle assembly grouped by SMIM36-low versus SMIM36-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM36→partner) and Y-score (partner→SMIM36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Spindle assembly →	+0.062	+0.230	<.001	<.001	3	17
STAD	Multicellular organism growth →	+0.045	+0.259	<.001	<.001	3	16
STAD	Mitotic G2/M transition checkpoint →	+0.058	+0.226	<.001	<.001	3	16
STAD	DNA-templated DNA replication maintenance of fidelity →	+0.052	+0.192	<.001	<.001	3	16
STAD	Regulation of DNA replication →	+0.057	+0.236	<.001	<.001	3	16
ESCA	Nuclear envelope organization →	+0.084	+0.354	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,698 associations by consensus.

Spindle assembly by SMIM36 expression — STAD

Explore this box plot interactively →