SMIM36

Across TCGA cell cohorts, SMIM36 RNA expression is significantly associated with the go_rna of many other GO terms, with 201 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SMIM36-associated GO terms across cancer lineages are Positive regulation of signal transduction by p53 class mediator, Fc-gamma receptor signaling pathway involved in phagocytosis, and Negative regulation of transforming growth factor beta1 production. Each is linked with SMIM36 in more than 2 cancer types. Because this analysis shows association rather than direction, both SMIM36-to-partner and partner-to-SMIM36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of signal transduction by p53 class mediator grouped by SMIM36-low versus SMIM36-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM36→partner) and Y-score (partner→SMIM36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of signal transduction by p53 class mediator →	+0.072	+0.084	.008	.007	3	3
LARGE_INTESTINE	Fc-gamma receptor signaling pathway involved in phagocytosis →	+0.077	+0.042	.003	.004	3	3
LUNG_NSCLC_LUAD	Negative regulation of transforming growth factor beta1 production →	+0.190	+0.096	<.001	.006	3	2
LUNG_NSCLC_LUAD	Negative regulation of amyloid precursor protein biosynthetic process →	+0.119	+0.127	<.001	.004	3	2
STOMACH	ER-nucleus signaling pathway →	+0.082	+0.085	.002	.007	3	2
OESOPHAGUS	Positive regulation of collagen fibril organization →	-0.209	-0.100	.005	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 201 associations by consensus.

Positive regulation of signal transduction by p53 class mediator by SMIM36 expression — STOMACH

Explore this box plot interactively →