SMIM34A

Across TCGA cell cohorts, SMIM34A RNA expression is significantly associated with the go_rna of many other GO terms, with 453 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SMIM34A-associated GO terms across cancer lineages are Immunoglobulin heavy chain V-D-J recombination, Regulation of ubiquitin-dependent protein catabolic process, and Positive regulation of mitotic cell cycle phase transition. Each is linked with SMIM34A in more than 4 cancer types. Because this analysis shows association rather than direction, both SMIM34A-to-partner and partner-to-SMIM34A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin heavy chain V-D-J recombination grouped by SMIM34A-low versus SMIM34A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM34A→partner) and Y-score (partner→SMIM34A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Immunoglobulin heavy chain V-D-J recombination →	-0.163	-0.062	.002	.008	3	4
CNS	Regulation of ubiquitin-dependent protein catabolic process →	+0.030	+0.044	<.001	.003	3	4
SOFT_TISSUE	Positive regulation of mitotic cell cycle phase transition →	-0.073	-0.018	.002	.002	1	5
BLOOD_Lymphoma	Late endosome to vacuole transport via multivesicular body sorting pathway →	+0.046	+0.108	<.001	.008	3	3
BLOOD_Lymphoma	Regulation of amino acid metabolic process →	+0.105	+0.112	<.001	.006	3	3
LUNG_NSCLC_LUAD	Positive regulation of cell cycle phase transition →	-0.045	-0.032	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 453 associations by consensus.

Immunoglobulin heavy chain V-D-J recombination by SMIM34A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →