SMIM26

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMIM26 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,994 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SMIM26-associated proteins across cancer lineages are CRNKL1, TMEM230, and XRN2. Each is linked with SMIM26 in more than 5 cancer types. Because this analysis shows association rather than direction, both SMIM26-to-partner and partner-to-SMIM26 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM26 versus CRNKL1 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM26→partner) and Y-score (partner→SMIM26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCRNKL1 →+0.288+0.483<.001<.00136
OVTMEM230 →+0.553+0.645.001.00135
COADXRN2 →+0.232+0.532<.001<.00135
PDACRBBP9 →+0.506+0.534<.001<.00135
LSCCESF1 →+0.480+0.471<.001<.00135
COADMAVS →+0.418+0.785<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,994 associations by consensus.

SMIM26 vs CRNKL1 — LSCC

Per-sample scatter of SMIM26 vs CRNKL1 in LSCC (Pearson r = 0.54).

Explore this scatter interactively →

Exploration