SMIM26

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMIM26 protein abundance is significantly associated with the RNA expression of many other genes, with 1,871 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SMIM26-associated genes across cancer lineages are AOPEP, TRNAU1AP, and LINC02507. Each is linked with SMIM26 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM26-to-partner and partner-to-SMIM26 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM26 versus AOPEP in UCEC, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM26→partner) and Y-score (partner→SMIM26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAOPEP →-0.707-0.575.003<.00132
BRCATRNAU1AP →-0.570-0.472.001.00132
LUADLINC02507 →-0.373-0.229<.001.00332
GBML3MBTL4-AS1 →-0.787-0.502.006.00832
BRCALINC01669 →-0.114-0.339.006.00632
HNSCSOS2 →-0.620-0.476.009<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,871 associations by consensus.

SMIM26 vs AOPEP — UCEC

Per-sample scatter of SMIM26 vs AOPEP in UCEC (Pearson r = -0.58).

Explore this scatter interactively →

Exploration