SMIM26

Across TCGA patient cohorts, SMIM26 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMIM26-associated genes across cancer lineages are FAM197Y1 and TAF9P1. Each is linked with SMIM26 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM26-to-partner and partner-to-SMIM26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM197Y1 grouped by SMIM26-low versus SMIM26-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM26→partner) and Y-score (partner→SMIM26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM197Y1 →	+0.049	+8.066	<.001	.007	3	1
UCEC	TAF9P1 →	+0.069	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

FAM197Y1 by SMIM26 expression — UCEC

Explore this box plot interactively →