SMIM26

Across TCGA cell cohorts, SMIM26 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,519 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMIM26-associated GO terms across cancer lineages are Positive regulation of anaphase-promoting complex-dependent catabolic process, Regulation of DNA-templated DNA replication, and Pyrimidine ribonucleoside diphosphate biosynthetic process. Each is linked with SMIM26 in more than 13 cancer types. Because this analysis shows association rather than direction, both SMIM26-to-partner and partner-to-SMIM26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of anaphase-promoting complex-dependent catabolic process grouped by SMIM26-low versus SMIM26-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM26→partner) and Y-score (partner→SMIM26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of anaphase-promoting complex-dependent catabolic process →	-0.162	-1.164	.001	.009	3	14
OESOPHAGUS	Regulation of DNA-templated DNA replication →	-0.100	-1.142	<.001	<.001	3	13
OESOPHAGUS	Pyrimidine ribonucleoside diphosphate biosynthetic process →	-0.124	-0.821	.004	.007	3	12
BONE	DNA replication proofreading →	-0.179	-0.652	<.001	.001	3	12
PANCREAS	Positive regulation of DNA replication →	-0.087	-1.003	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Protein depolymerization →	-0.122	-1.184	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,519 associations by consensus.

Positive regulation of anaphase-promoting complex-dependent catabolic process by SMIM26 expression — STOMACH

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