SMIM15-AS1

Across TCGA pan-cancer cohorts, SMIM15-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of SMIM15-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where SMIM15-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SMIM15-AS1 is over-expressed in tumor, although a few such as UCEC and THCA show the opposite, repressed pattern.

PAAD, LIHC, and UCEC are the cancer types where SMIM15-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SMIM15-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PAAD	All	All	+0.487	.027	6	view →
LIHC	Male	All	+0.131	<.001	6	view →
UCEC	All	All	−0.317	.013	2	view →
THCA	All	All	−0.166	.003	2	view →
HNSC	Male	All	+0.152	.015	2	view →
CHOL	All	All	+0.307	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

SMIM15-AS1–PAAD

Open the PAAD breakdown →