SMIM10L1

Across TCGA patient cohorts, SMIM10L1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMIM10L1-associated genes across cancer lineages are LINC00265-2P and MIR6857. Each is linked with SMIM10L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM10L1-to-partner and partner-to-SMIM10L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00265-2P grouped by SMIM10L1-low versus SMIM10L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM10L1→partner) and Y-score (partner→SMIM10L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC00265-2P →	+0.133	+5.031	<.001	.009	3	1
UCEC	MIR6857 →	+0.626	+5.358	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

LINC00265-2P by SMIM10L1 expression — UCEC

Explore this box plot interactively →