SMIM1

Across TCGA patient cohorts, SMIM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,754 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SMIM1-associated proteins across cancer lineages are CDK18_S89, CDK18_S98, and FBXO2. Each is linked with SMIM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SMIM1-to-partner and partner-to-SMIM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM1 versus CDK18_S89 in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM1→partner) and Y-score (partner→SMIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CDK18_S89 →	+0.731	+0.541	.001	<.001	3	4
LSCC	CDK18_S98 →	+0.629	+0.432	.004	.001	3	4
OV	FBXO2 →	+1.120	+0.841	<.001	<.001	3	4
CCRCC	PKP4_S776 →	+0.609	+0.619	.003	.002	3	4
LUAD	SMIM1_S17 →	+1.007	+1.068	.009	.008	3	4
OV	TUBB4A →	+1.187	+0.936	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,754 associations by consensus.

SMIM1 vs CDK18_S89 — GBM

Explore this scatter interactively →