SMG9

Across TCGA patient cohorts, SMG9 protein abundance is significantly associated with the RNA expression of many other genes, with 5,358 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SMG9-associated genes across cancer lineages are MYCT1, DIPK2B, and SHE. Each is linked with SMG9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SMG9-to-partner and partner-to-SMG9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMG9 versus MYCT1 in CCRCC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMG9→partner) and Y-score (partner→SMG9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MYCT1 →	-0.960	-0.169	<.001	<.001	3	3
CCRCC	DIPK2B →	-0.748	-0.138	.003	.005	3	3
CCRCC	SHE →	-0.723	-0.161	.002	.005	3	3
UCEC	RNU7-154P →	-1.359	-0.118	<.001	.009	3	3
LSCC	UBA2 →	+0.420	+0.084	<.001	.002	3	3
GBM	FAAH →	-0.738	-0.166	.006	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,358 associations by consensus.

SMG9 vs MYCT1 — CCRCC

Explore this scatter interactively →