SMG9

Across TCGA cell cohorts, SMG9 protein abundance is significantly associated with the RNA expression of many other genes, with 3,696 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMG9-associated genes across cancer lineages are MDN1, DHX58, and CDKN2D. Each is linked with SMG9 in more than 5 cancer types. Because this analysis shows association rather than direction, both SMG9-to-partner and partner-to-SMG9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMG9 versus MDN1 in LUNG_SCLC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMG9→partner) and Y-score (partner→SMG9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	MDN1 →	+0.880	+0.636	.004	.006	3	6
BLOOD_Leukemia	DHX58 →	-1.502	-1.253	<.001	<.001	3	5
LUNG_SCLC	CDKN2D →	-1.696	-0.630	<.001	<.001	3	5
BLOOD_Leukemia	DNAJB2 →	-0.745	-0.780	.003	.001	3	5
BLOOD_Leukemia	GDI1 →	-0.977	-1.133	<.001	.001	3	5
BLOOD_Leukemia	FAM3A →	-0.794	-1.183	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,696 associations by consensus.

SMG9 vs MDN1 — LUNG_SCLC

Explore this scatter interactively →