SMG7

Across TCGA patient cohorts, SMG7 RNA expression is significantly associated with the RNA expression of many other genes, with 20,829 significant associations in total. ACC shows the largest number of these associations.

The most reproducible SMG7-associated genes across cancer lineages are KMT2A, ANKRD17, and REV1. Each is linked with SMG7 in more than 33 cancer types. Because this analysis shows association rather than direction, both SMG7-to-partner and partner-to-SMG7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMG7 versus KMT2A in DLBC, with a Pearson correlation of 0.79.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMG7→partner) and Y-score (partner→SMG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	KMT2A →	+1.143	+0.966	<.001	<.001	3	34
DLBC	ANKRD17 →	+1.440	+0.945	<.001	<.001	3	34
UVM	REV1 →	+1.503	+0.728	<.001	<.001	3	34
DLBC	NAB1 →	+1.285	+0.759	<.001	<.001	3	34
UCS	TRIM41 →	+0.912	+0.786	<.001	<.001	3	34
KIRP	RNF111 →	+1.106	+0.823	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,829 associations by consensus.

SMG7 vs KMT2A — DLBC

Explore this scatter interactively →