Across TCGA patient cohorts, SMG1P4 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMG1P4-associated genes across cancer lineages are IRX5, P2RY8, and RNU6-888P. Each is linked with SMG1P4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMG1P4-to-partner and partner-to-SMG1P4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMG1P4→partner) and Y-score (partner→SMG1P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IRX5 →	+1.037	+3.201	.003	.009	3	1
UCEC	P2RY8 →	+0.768	+3.354	.001	.005	3	1
UCEC	RNU6-888P →	+0.333	+2.611	.004	.009	3	1
UCEC	RNY4P27 →	+0.282	+4.038	<.001	.001	3	1
UCEC	RNA5SP509 →	+0.251	+4.566	<.001	.003	3	1
UCEC	RNU1-57P →	+0.217	+4.300	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration

SMG1P4 survival (RNA) · tumor vs normal (RNA) · all SMG1P4 data types