Across TCGA patient cohorts, SMG1P2 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMG1P2-associated genes across cancer lineages are MIR6129, LINC02348, and RNA5SP414. Each is linked with SMG1P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMG1P2-to-partner and partner-to-SMG1P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMG1P2→partner) and Y-score (partner→SMG1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6129 →	+0.599	+3.496	<.001	.005	3	1
UCEC	LINC02348 →	+0.530	+3.778	.002	.006	3	1
UCEC	RNA5SP414 →	+1.085	+4.255	<.001	<.001	3	1
UCEC	RNA5SP411 →	+2.281	+4.715	<.001	<.001	3	1
UCEC	RNA5SP412 →	+0.866	+3.967	.001	.001	3	1
UCEC	MIR6509 →	+0.853	+3.277	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

SMG1P2 survival (RNA) · tumor vs normal (RNA) · all SMG1P2 data types