SMCP

Across TCGA cell cohorts, SMCP mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SMCP-associated genes across cancer lineages are OR4D5 and CCL18. Each is linked with SMCP in more than 1 cancer types. Because this analysis shows association rather than direction, both SMCP-to-partner and partner-to-SMCP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4D5 grouped by SMCP-low versus SMCP-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMCP→partner) and Y-score (partner→SMCP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR4D5 →	+0.014	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	CCL18 →	+0.026	+4.212	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR4D5 by SMCP expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →