SMC5-AS1

Across TCGA patient cohorts, SMC5-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,566 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SMC5-AS1-associated proteins across cancer lineages are SEC63, EPM2AIP1, and GNAQ. Each is linked with SMC5-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMC5-AS1-to-partner and partner-to-SMC5-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMC5-AS1 versus SEC63 in CCRCC, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMC5-AS1→partner) and Y-score (partner→SMC5-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SEC63 →	-0.251	-0.324	<.001	<.001	3	5
CCRCC	EPM2AIP1 →	+0.309	+0.528	<.001	<.001	3	5
BRCA	GNAQ →	+0.392	+0.301	.002	.001	3	4
OV	C9orf64 →	+0.425	+0.660	<.001	<.001	3	4
LUAD	RPL5 →	-0.216	-0.695	<.001	<.001	3	4
LUAD	RPS3A →	-0.174	-0.560	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,566 associations by consensus.

SMC5-AS1 vs SEC63 — CCRCC

Explore this scatter interactively →