SMC1B

Across TCGA cell cohorts, SMC1B RNA expression is significantly associated with the RNA expression of many other genes, with 2,000 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SMC1B-associated genes across cancer lineages are RIBC2, CBY3, and NHLRC1. Each is linked with SMC1B in more than 12 cancer types. Because this analysis shows association rather than direction, both SMC1B-to-partner and partner-to-SMC1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMC1B versus RIBC2 in URINARY_TRACT, with a Pearson correlation of 0.50.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMC1B→partner) and Y-score (partner→SMC1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	RIBC2 →	+2.337	+1.029	<.001	.008	2	13
OVARY	CBY3 →	+0.630	+1.122	<.001	<.001	2	6
LUNG_SCLC	NHLRC1 →	+1.241	+1.265	<.001	.001	3	5
OVARY	TSPYL5 →	+2.723	+1.015	<.001	<.001	3	3
LUNG_SCLC	SLFN13 →	+3.503	+1.593	<.001	<.001	3	3
LUNG_SCLC	MEIOC →	+1.503	+1.197	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,000 associations by consensus.

SMC1B vs RIBC2 — URINARY_TRACT

Explore this scatter interactively →