SMARCE1

Across TCGA cell cohorts, SMARCE1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,055 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMARCE1-associated genes across cancer lineages are HDDC2, ERAS, and CAPS2. Each is linked with SMARCE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMARCE1-to-partner and partner-to-SMARCE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCE1 versus HDDC2 in PANCREAS, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCE1→partner) and Y-score (partner→SMARCE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	HDDC2 →	-1.049	-0.857	.007	.008	3	5
LUNG_SCLC	ERAS →	+0.272	+0.843	<.001	.002	3	4
SOFT_TISSUE	CAPS2 →	-2.168	-1.398	<.001	<.001	3	4
PANCREAS	WDR36 →	-0.562	-0.760	.003	.003	3	4
LIVER	UQCRQ →	-0.425	-0.907	.002	.002	3	3
LIVER	KIF13B →	+1.734	+0.926	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,055 associations by consensus.

SMARCE1 vs HDDC2 — PANCREAS

Explore this scatter interactively →