SMARCE1

Across TCGA cell cohorts, SMARCE1 protein abundance is significantly associated with the go_rna of many other GO terms, with 3,281 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMARCE1-associated GO terms across cancer lineages are Epigenetic programming of gene expression, Ventricular cardiac muscle tissue development, and Positive regulation of glycogen catabolic process. Each is linked with SMARCE1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SMARCE1-to-partner and partner-to-SMARCE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic programming of gene expression grouped by SMARCE1-low versus SMARCE1-high in LUNG_NSCLC_LUSC.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCE1→partner) and Y-score (partner→SMARCE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Epigenetic programming of gene expression →	+0.106	+1.317	<.001	.004	3	4
OESOPHAGUS	Ventricular cardiac muscle tissue development →	+0.117	+1.621	.003	.005	3	4
SOFT_TISSUE	Positive regulation of glycogen catabolic process →	+0.233	+1.449	.003	<.001	3	4
SOFT_TISSUE	Detoxification of inorganic compound →	-0.237	-1.782	.008	.001	3	4
BONE	Myeloid leukocyte differentiation →	-0.124	-1.962	.001	.009	3	3
LUNG_NSCLC_LUSC	Regulation of skeletal muscle cell differentiation →	+0.157	+2.093	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,281 associations by consensus.

Epigenetic programming of gene expression by SMARCE1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →