SMARCD3

Across TCGA patient cohorts, SMARCD3 protein abundance is significantly associated with the RNA expression of many other genes, with 13,009 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMARCD3-associated genes across cancer lineages are EFNB3, ARHGEF25, and SLC22A17. Each is linked with SMARCD3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMARCD3-to-partner and partner-to-SMARCD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCD3 versus EFNB3 in OV, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCD3→partner) and Y-score (partner→SMARCD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EFNB3 →	+1.292	+0.662	<.001	<.001	3	5
BRCA	ARHGEF25 →	+0.528	+0.404	.002	<.001	3	5
OV	SLC22A17 →	+0.872	+0.517	<.001	.003	3	5
GBM	NRXN2 →	+1.015	+0.290	<.001	<.001	3	4
OV	DZIP1 →	+0.759	+0.468	.003	.008	3	4
GBM	ADAMTS10 →	+0.737	+0.389	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,009 associations by consensus.

SMARCD3 vs EFNB3 — OV

Explore this scatter interactively →