SMARCD3

Across TCGA cell cohorts, SMARCD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,103 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SMARCD3-associated GO terms across cancer lineages are IMP salvage, Regulation of smooth muscle cell differentiation, and Heart contraction. Each is linked with SMARCD3 in more than 12 cancer types. Because this analysis shows association rather than direction, both SMARCD3-to-partner and partner-to-SMARCD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP salvage grouped by SMARCD3-low versus SMARCD3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCD3→partner) and Y-score (partner→SMARCD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	IMP salvage →	+0.238	+1.779	<.001	.001	3	13
BONE	Regulation of smooth muscle cell differentiation →	+0.158	+1.811	.001	.001	3	13
OESOPHAGUS	Heart contraction →	-0.158	-1.515	<.001	.004	3	13
OESOPHAGUS	Establishment of protein localization to organelle →	+0.081	+2.122	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.108	+1.257	<.001	<.001	3	13
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.073	+1.253	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,103 associations by consensus.

IMP salvage by SMARCD3 expression — LUNG_SCLC

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