SMARCD1

Across TCGA patient cohorts, SMARCD1 mutation is significantly associated with the RNA expression of many other genes, with 384 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMARCD1-associated genes across cancer lineages are MIR5696, RPL23AP94, and SMSP1. Each is linked with SMARCD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMARCD1-to-partner and partner-to-SMARCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5696 grouped by SMARCD1-low versus SMARCD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCD1→partner) and Y-score (partner→SMARCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR5696 →	+0.210	+3.197	<.001	<.001	3	2
UCEC	RPL23AP94 →	+0.156	+1.810	.001	.002	3	2
BLCA	SMSP1 →	+0.038	+3.850	<.001	.004	3	2
BLCA	RN7SL402P →	+0.174	+3.715	.005	.003	3	2
BLCA	RNU6-911P →	+0.477	+3.478	<.001	.005	3	2
READ	CDRT15P8 →	+0.092	+4.421	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 384 associations by consensus.

MIR5696 by SMARCD1 expression — UCEC

Explore this box plot interactively →