SMARCC1

Across TCGA patient cohorts, SMARCC1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,371 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SMARCC1-associated genes across cancer lineages are MCM3, KIF15, and CDC25A. Each is linked with SMARCC1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SMARCC1-to-partner and partner-to-SMARCC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCC1 versus MCM3 in HNSC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCC1→partner) and Y-score (partner→SMARCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MCM3 →	+0.936	+0.300	.004	<.001	3	9
GBM	KIF15 →	+1.171	+0.436	<.001	<.001	3	9
OV	CDC25A →	+1.082	+0.454	<.001	<.001	3	9
UCEC	TRAIP →	+1.094	+0.411	<.001	<.001	3	9
LUAD	TTK →	+1.109	+0.345	<.001	<.001	3	8
UCEC	NEK2 →	+1.157	+0.323	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,371 associations by consensus.

SMARCC1 vs MCM3 — HNSC

Explore this scatter interactively →