SMARCAL1-AS1

Across TCGA pan-cancer cohorts, SMARCAL1-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of SMARCAL1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SMARCAL1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types SMARCAL1-AS1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and LIHC are the cancer types where SMARCAL1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SMARCAL1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.085	.001	6	view →
KICH	All	All	−0.158	.013	4	view →
LIHC	Female	All	−0.113	.001	2	view →
BLCA	All	All	+0.050	.043	2	view →
CHOL	Male	All	−0.113	.003	1	view →
HNSC	All	IV	+0.025	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

SMARCAL1-AS1–KIRC

Open the KIRC breakdown →