SMARCA5

Across TCGA cell cohorts, SMARCA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,819 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMARCA5-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Regulation of chromosome condensation, and Negative regulation of gene expression, epigenetic. Each is linked with SMARCA5 in more than 19 cancer types. Because this analysis shows association rather than direction, both SMARCA5-to-partner and partner-to-SMARCA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome condensation grouped by SMARCA5-low versus SMARCA5-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCA5→partner) and Y-score (partner→SMARCA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of chromosome condensation →	+0.162	+0.721	<.001	<.001	3	20
OESOPHAGUS	Regulation of chromosome condensation →	+0.202	+0.668	.006	.004	3	18
OVARY	Negative regulation of gene expression, epigenetic →	+0.075	+0.610	<.001	.003	3	17
SKIN	Positive regulation of organelle assembly →	+0.058	+0.525	<.001	.002	3	16
OVARY	Mitotic sister chromatid cohesion →	+0.139	+0.811	<.001	<.001	3	16
BREAST	Protein branched polyubiquitination →	+0.117	+0.701	<.001	.003	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,819 associations by consensus.

Negative regulation of chromosome condensation by SMARCA5 expression — SOFT_TISSUE

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