SMARCA4

Across TCGA patient cohorts, SMARCA4 protein abundance is significantly associated with the RNA expression of many other genes, with 18,971 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMARCA4-associated genes across cancer lineages are BEND3, CBX2, and RFC5. Each is linked with SMARCA4 in more than 7 cancer types. Because this analysis shows association rather than direction, both SMARCA4-to-partner and partner-to-SMARCA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCA4 versus BEND3 in LUAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCA4→partner) and Y-score (partner→SMARCA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BEND3 →	+0.752	+0.408	<.001	<.001	3	8
BRCA	CBX2 →	+1.327	+0.322	.001	<.001	3	8
LSCC	RFC5 →	+0.880	+0.418	<.001	<.001	3	8
LSCC	TIMELESS →	+1.077	+0.531	<.001	<.001	3	8
GBM	ATP8B4 →	-0.924	-0.386	<.001	<.001	3	7
LSCC	TMEM97 →	+1.140	+0.407	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,971 associations by consensus.

SMARCA4 vs BEND3 — LUAD

Explore this scatter interactively →