SMARCA4

Across TCGA patient cohorts, SMARCA4 protein abundance is significantly associated with the protein abundance of many other proteins, with 31,882 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMARCA4-associated proteins across cancer lineages are CPSF1, CTR9, and DDX5. Each is linked with SMARCA4 in more than 9 cancer types. Because this analysis shows association rather than direction, both SMARCA4-to-partner and partner-to-SMARCA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCA4 versus CPSF1 in GBM, with a Pearson correlation of 0.72.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCA4→partner) and Y-score (partner→SMARCA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CPSF1 →	+0.271	+0.409	<.001	<.001	3	10
LSCC	CTR9 →	+0.266	+0.481	<.001	<.001	3	10
GBM	DDX5 →	+0.325	+0.367	<.001	<.001	3	10
BRCA	RBM17 →	+0.277	+0.321	<.001	<.001	3	10
OV	INTS1 →	+0.231	+0.356	<.001	<.001	3	10
GBM	KHDRBS1 →	+0.307	+0.419	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 31,882 associations by consensus.

SMARCA4 vs CPSF1 — GBM

Explore this scatter interactively →