SMAD5-AS1

Across TCGA patient cohorts, SMAD5-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,091 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SMAD5-AS1-associated GO terms across cancer lineages are U2-type prespliceosome assembly, Oxidative phosphorylation, and Outer mitochondrial membrane organization. Each is linked with SMAD5-AS1 in more than 14 cancer types. Because this analysis shows association rather than direction, both SMAD5-AS1-to-partner and partner-to-SMAD5-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, U2-type prespliceosome assembly grouped by SMAD5-AS1-low versus SMAD5-AS1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMAD5-AS1→partner) and Y-score (partner→SMAD5-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	U2-type prespliceosome assembly →	+0.067	+0.073	<.001	<.001	3	14
STAD	Oxidative phosphorylation →	+0.056	+0.079	<.001	<.001	2	15
ACC	Outer mitochondrial membrane organization →	+0.044	+0.197	<.001	.003	2	14
STAD	Mitochondrial translation →	+0.056	+0.084	<.001	<.001	3	13
STAD	Mitochondrial respiratory chain complex assembly →	+0.059	+0.095	<.001	<.001	3	13
STAD	ATP synthesis coupled electron transport →	+0.058	+0.086	<.001	<.001	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,091 associations by consensus.

U2-type prespliceosome assembly by SMAD5-AS1 expression — STAD

Explore this box plot interactively →