SLX4IP

Across TCGA cell cohorts, SLX4IP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,053 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLX4IP-associated GO terms across cancer lineages are Regulation of alternative mRNA splicing, via spliceosome, Promoter clearance during DNA-templated transcription, and RNA polymerase II promoter clearance. Each is linked with SLX4IP in more than 12 cancer types. Because this analysis shows association rather than direction, both SLX4IP-to-partner and partner-to-SLX4IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of alternative mRNA splicing, via spliceosome grouped by SLX4IP-low versus SLX4IP-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLX4IP→partner) and Y-score (partner→SLX4IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of alternative mRNA splicing, via spliceosome →	+0.090	+0.643	<.001	.002	3	13
OVARY	Promoter clearance during DNA-templated transcription →	+0.108	+0.699	<.001	<.001	3	13
OVARY	RNA polymerase II promoter clearance →	+0.108	+0.699	<.001	<.001	3	13
URINARY_TRACT	Cilium or flagellum-dependent cell motility →	-0.075	-0.434	.005	.009	3	12
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.111	-0.636	<.001	.003	3	12
URINARY_TRACT	Cilium-dependent cell motility →	-0.075	-0.434	.005	.009	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,053 associations by consensus.

Regulation of alternative mRNA splicing, via spliceosome by SLX4IP expression — SOFT_TISSUE

Explore this box plot interactively →