Across TCGA patient cohorts, SLX4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,994 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLX4-associated proteins across cancer lineages are MAST4_S1523, SLX4IP_S396, and MTA1_S576. Each is linked with SLX4 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLX4-to-partner and partner-to-SLX4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLX4→partner) and Y-score (partner→SLX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MAST4_S1523 →	-0.532	-0.349	<.001	<.001	3	5
GBM	SLX4IP_S396 →	+0.654	+0.489	<.001	<.001	3	5
LSCC	MTA1_S576 →	+0.779	+0.449	<.001	<.001	3	4
LUAD	NASP_S480 →	+0.997	+0.460	<.001	<.001	3	4
LSCC	ARHGAP30_S1086 →	-0.737	-0.462	.005	.003	3	4
LUAD	PDS5A_T1208 →	+0.549	+0.526	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,994 associations by consensus.

Exploration

SLX4 survival (RNA) · tumor vs normal (RNA) · all SLX4 data types